IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells
نویسندگان
چکیده
منابع مشابه
IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells.
Shigella proteins that are targeted to host cells by a type III secretion apparatus are essential for reorganization of the cytoskeleton during cell invasion. We have developed a semi-permeabilized cell assay that tests the effects of bacterial proteins on the actin cytoskeleton. The Shigella IpaC protein was found to induce the formation of filopodial and lamellipodial extensions in these semi...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 1999
ISSN: 1460-2075
DOI: 10.1093/emboj/18.12.3249